Considering running a game of Hc Svnt Dracones, a sci-fi post-humanist RPG set 700 years after the downfall of humanity. It has undertones of Shadowrun and Call of Cthulu running through it, with large MegaCorps that run the solar system, and otherworldly entities threatening from the shadows.
"HC SVNT DRACONES puts you in the body of a human experiment that outlived its creator, and has gone on expanding into the galaxy while trying to heed the lessons of a race that fell to ruin. It's about exploration and fear, expansion and conquest, intrigue and subterfuge, and ultimately, it’s about you, learning to be you, when all the trappings of humanity you define yourself with are dead and gone."
While the game system has a lot of furries in it, it is less about being a furry and more about finding your own place in the universe, after your creators are long gone. The character creation system allows for a lot of flexability as well, with such things as Laterals (feral bodies, inteligent minds), Taurs and Hemi-Vectors (Japanese cat-girls, fox-girls, etc.)
"HC SVNT DRACONES puts you in the body of a human experiment that outlived its creator, and has gone on expanding into the galaxy while trying to heed the lessons of a race that fell to ruin. It's about exploration and fear, expansion and conquest, intrigue and subterfuge, and ultimately, it’s about you, learning to be you, when all the trappings of humanity you define yourself with are dead and gone."
While the game system has a lot of furries in it, it is less about being a furry and more about finding your own place in the universe, after your creators are long gone. The character creation system allows for a lot of flexability as well, with such things as Laterals (feral bodies, inteligent minds), Taurs and Hemi-Vectors (Japanese cat-girls, fox-girls, etc.)