So I've played partway through and have been having a good time for the most part, but wanted to chime in with some feedback!
Stamina
The stamina system is annoying, but I definitely don't think it's unworkable. I think significantly reducing or even removing the delay before stamina regen starts would go a long way to making it feel like the player doesn't have to just stop doing anything and disengage as often. If you wanted you could even tack on those seconds onto the regeneration time, keeping the time it'd take to regen from empty to full functionally the same!
This would make it so you can still take an occasional swing to deflect a projectile or hit a singular enemy and not have to wait a few seconds to get ANY stamina back. Cause currently the only good way to regen stamina is to just disengage from combat completely. This is the thing I feel most strongly about in my feedback as I really think this simple change would enable players to be more active while waiting for stamina regen.
Corruption
I think the corruption is fine, but there should be a way to clear it at base for a cost or something. If there's no easy way for you to implement that then I'd re-enable the plant. It feels really weird to deliberately kill myself because I messed up and don't wanna bother going into going into the next area half dead. I've honestly I've just taken to cheating the value back down to 0 to spare myself the tedium and I'm not even half way through the game yet.
Return to Base Cost
I think I get what you were going for with this, I really do, but I don't think it has the desired effect on gameplay. It's basically a tax on the player's funds and encourages running multiple levels in a row. Seems neat on the surface cause then you might have people taking risks to get more money, but I think the outcome is more of "I'm going to repeat the first 2-3 levels a dozen times until I have all the money I need and then clear all my status effects at once". I think this just encourages memorization of levels, which while it is certainly a skill that can be worthwhile to test players on, there's nothing encouraging players to ever grind anything but the first few levels. Making it an exercise in tedium.
Slime Status
I miss being able to run around cum covered all the time. It slows me down too much now though. ;~;
(Would be nice to have a way to have it on continuously, maybe with less speed reduction though)
Fun tho, I'm gonna keep playin' and am really lookin' forward to 1.1!
EDIT: Thank you for giving me an excuse to play this again
EDIT2: Hey, after a bit of testing I think I've realized that having arousal (the pink bar) makes the duration the struggle bar is pink increase? If that's correct, I recommend removing that, as it's double dipping into the stamina and makes low stamina which already feels bad feel even worse. It really incentivizes players to play in an overly cautious way and is a mechanic that isn't communicated clearly which may lead some people to think it's just the system in general that is messed up. In my experience making games I've found that double dipping with punishment mechanics needs to be done exceedingly carefully otherwise it leads to frustration really quickly. Better to just go with one of them but harsher if you really want it to be punishing but still feel okay.
(I could be wrong about arousal doing this and thus this entire paragraph though w)