Hehe, that's what we always do, store everything useful in the chest, thinking that we need it later, all the way until After we beat the last boss.
Well, this game is based on Rogue-like, in a sense that, whatever you do, you can Never Be Ultimately Overpowered.
You can, however, be somewhat, but not entirely, OP to a specific Stage you're gonna play.
If you opt out your equipment to be a fully Assault-type ( ATK and VIT or DEF ), then you are in for a world of pain when the seemingly week monsters throws status debuffs and status ailment on you.
Here are a list of the things you need to ponder ( in general sense ) when spelunking on a much deeper floors:
- Offensive Power Vs Defensive Power
- Does it contain monsters with Status Ailment you are weak against? ( especially Paralysis, Binding, & Knockdown, to name a few )
- Status Debuffs ( Decelerate from Belle, AGI Down from Black Goat, Cyclops, Abyss Toad, Belle )
- Sex-Kind ( Though if you maintain purity, then this will pose much less significance )
- Surrounded, flanked, or just fighting 3 Black Dogs Lvl 100+ or Dullahan Lvl 100+ ( who kept traversing inside an effing wall ) Without Scrolls, Guns and Potions.
- Monsters with Equipment durability break attacks