What builds are you guys going for? And how are you faring?
I set Sensitivity Cock to max, let Ass at default, and minimized all other sensitivities. Later I use the item that gives +5 spirit and +75% cock sensitivity. As I already avoid sex said drawback is almost irrelevant. Fetish to ass, but that's more of a personal preferences. The only perk I've chosen is the +5 to energy every time you use Caress.
In my latest playthrough I increased Luck to 20 for the secret event in the forest, then increased the other four stats evenly; only increased arousal once for one specific willpower trial.
Important skills are Magic > Analyze,, Magic > Magical Binding, Pain > Bondage Net, and Seduction > Distract. By alterntaing between the appropriate handcuff skill and Caress you can beat any single opponent with a weakness to Pain or Magic easily. Distract is very important to get out of binds if Push Away does not work, as this build succumbs to sex very easily.
So far, I had no major problems against all monster girls, only against the dual battle with the two end bosses of the temple I had to use an item to remove the entranced debuff once.
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Threshold:
The game seems to miss monster girls who abuse sensitivity to ass.
And a glaring bug seems to be that you can buy skills even though you meet their requirement only because of items. This makes it possible to buy and use most skills even before you should be able to use them.