Re: Rune's Pharmacy [RJ139385]
Lowering the graphics to 8-bit colour depth will almost certainly not effect the quality. The reason? Monitors tend to cap out at 8-bit colour depth. The article I linked is a little old these days, as some fairly expensive 10-bit monitors exist as well, but the point basically stands. For most people, there will be no difference between 32-bit and 8-bit colour depth, unless you want to start printing the CGs on a decent laser printer (these can have surprisingly good colour depth).
You wrote something so absurdly wrong that I had to login just to correct you.
You confused total colours, with colours PER CHANNEL.
Most modern monitors are limited to 6 bit PER CHANNEL, meaning you get 64 shades of blue, 64 shades of green, and 64 shades of red.
But if you mix up all those shades, you end with 262144 colours.
8-bit images can only do 256 colours (per image, not per screen), so changing images to 8-bit DOES reduce quality, specially in highly complex backgrounds and whatnot, usually not obvious in heavily sprite-based games.
8-bit colours per channel monitors can do 16777216 colours.
32-bit images can do 4294967296 colours.
10-bit per channel monitors can do 1073741824 colours.
Some CRTs could do more than 10-bit per channel, with the highest tested limit being 16-bit per channel, that monitor could render images with 281474976710656 colours.